GLP-1 Medication: Frequently Asked Questions
Answers to the most common questions about semaglutide, tirzepatide, compounded GLP-1 medications, online weight loss treatment, cost, safety, and how Ozari Health works.
How GLP-1 Treatment Works
What is GLP-1 medication and how does it cause weight loss?
GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications that mimic a hormone naturally produced in the gut after eating. They slow gastric emptying, reduce appetite signals in the brain, and regulate blood sugar — leading to significant, sustained weight loss. Semaglutide and tirzepatide are the two most prescribed GLP-1 medications available today.
What's the difference between semaglutide and tirzepatide?
Semaglutide activates one metabolic pathway (GLP-1), while tirzepatide activates two (GLP-1 and GIP). In clinical trials, tirzepatide produced greater average weight loss — up to 22% of body weight versus 15% for semaglutide. Both are effective; your provider will recommend the right option based on your health history and goals.
What is the difference between compounded semaglutide and Ozempic or Wegovy?
Ozempic and Wegovy are brand-name semaglutide products manufactured by Novo Nordisk. Compounded semaglutide contains the same active molecule but is prepared by licensed US compounding pharmacies to exact prescribed doses. Compounded versions are significantly more affordable and have been widely prescribed during periods of brand-name shortage.
Is compounded semaglutide legal?
Yes. Compounded semaglutide is legally prescribed and dispensed when prepared by a licensed 503B outsourcing facility or a licensed 503A compounding pharmacy. Ozari works exclusively with licensed US pharmacies that meet all federal and state compounding standards.
How does online GLP-1 treatment work at Ozari Health?
You complete a digital health intake in under 10 minutes. A licensed physician reviews your medical history, goals, and eligibility — typically within 24–48 hours. If approved, your prescription is sent to a partner pharmacy and shipped directly to your door. You have ongoing access to your care team for dose adjustments and support throughout treatment.
Eligibility & Getting Started
Who qualifies for GLP-1 medication?
GLP-1 medications are approved for adults with a BMI of 30 or higher, or 27+ with at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol. Your Ozari provider will conduct a full medical review to confirm eligibility.
Do I need to see a doctor in person to get semaglutide or tirzepatide?
No. Ozari is a fully online telehealth platform. You never need an in-person visit. A licensed physician reviews your intake remotely and, if appropriate, issues a prescription that is filled and shipped directly to you.
Can I get semaglutide prescribed online without insurance?
Yes. Ozari does not require insurance. Treatment starts at $86/month with transparent flat-rate pricing — no hidden fees, no prior authorizations, and no pharmacy copays. Free shipping is included.
What conditions disqualify someone from GLP-1 treatment?
GLP-1 medications are not appropriate for individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), active pancreatitis, severe gastrointestinal conditions, or who are currently pregnant or breastfeeding. Your provider will review your full history before prescribing.
How long does it take to get started with Ozari?
Most patients complete intake in under 10 minutes. Provider review typically takes 24–48 hours. Once approved, your prescription ships within 1–2 business days and arrives within 3–5 business days. Most patients receive their first dose within one week of signing up.
Results & Expectations
How much weight can I lose on semaglutide?
In the STEP clinical trials, patients on semaglutide lost an average of 15% of their body weight over 68 weeks. Some patients lost 20% or more. Results depend on dosage, adherence, and lifestyle factors. Your provider will help you set realistic expectations based on your starting point.
How much weight can I lose on tirzepatide?
In the SURMOUNT clinical trials, patients on tirzepatide lost an average of 20–22% of their body weight — with some participants losing over 25%. Tirzepatide's dual-pathway mechanism makes it the highest-performing GLP-1 medication currently available.
How long does it take to see results on GLP-1 medication?
Most patients notice reduced appetite within the first 1–2 weeks. Visible weight loss typically begins by weeks 4–8 as your dose is titrated upward. Significant results — 10%+ body weight reduction — are commonly reported between months 3 and 6.
Will I regain weight if I stop taking GLP-1 medication?
Clinical data shows that weight regain is common after stopping GLP-1 therapy without lifestyle changes in place. Many patients continue at a maintenance dose long-term. Your Ozari provider will help you plan a sustainable exit strategy or tapering schedule when the time comes.
Do I need to diet or exercise for GLP-1 medication to work?
No strict diet or exercise program is required. GLP-1 medications reduce appetite significantly on their own. However, prioritizing protein intake and incorporating light resistance training will help preserve muscle mass and maximize long-term results.
Safety & Side Effects
What are the most common side effects of semaglutide and tirzepatide?
The most frequently reported side effects are gastrointestinal: nausea, constipation, diarrhea, and mild fatigue — particularly during dose increases. These typically resolve within 2–4 weeks as your body adjusts. Your provider can slow titration to minimize discomfort.
Is compounded semaglutide safe?
Compounded semaglutide prepared by licensed pharmacies uses pharmaceutical-grade active ingredients and undergoes rigorous quality testing. Ozari works exclusively with pharmacies that meet federal 503A and 503B compounding standards. Your provider monitors your response throughout treatment.
Can I drink alcohol while taking semaglutide or tirzepatide?
Alcohol isn't prohibited, but it can worsen nausea and gastrointestinal side effects and may slow weight loss progress. Many patients naturally reduce alcohol consumption on GLP-1 therapy due to decreased appetite and changed tolerance.
Will I lose muscle mass on GLP-1 medication?
Some lean mass loss can occur with any significant caloric deficit. To protect muscle, prioritize protein intake (0.7–1g per pound of goal body weight daily) and incorporate resistance training 2–3 times per week. Your Ozari care team provides personalized guidance on preserving lean mass.
Are GLP-1 medications safe for long-term use?
Yes. Semaglutide and tirzepatide have been studied in multi-year clinical trials and are well-established for long-term use under medical supervision. The STEP and SURMOUNT trials followed patients for up to 2 years with strong safety profiles.
Cost, Insurance & Billing
How much does semaglutide cost per month without insurance?
At Ozari Health, compounded semaglutide starts at $86/month. This includes the medication, provider consultation, and free shipping — with no insurance required and no hidden fees. Brand-name Ozempic or Wegovy can cost $900–$1,400/month without insurance coverage.
Does insurance cover compounded semaglutide or tirzepatide?
Most insurance plans do not cover compounded GLP-1 medications. Brand-name versions like Ozempic, Wegovy, Mounjaro, and Zepbound may have coverage depending on your plan and diagnosis. Ozari's cash-pay model is designed to make treatment accessible without insurance.
Is there a contract or long-term commitment?
No. Ozari operates on a month-to-month subscription. You can cancel at any time with no penalties or cancellation fees. We do not lock patients into long-term contracts.
What is Ozari's refund policy?
Once a prescription is approved and transmitted to the pharmacy for fulfillment, charges are non-refundable. If a provider determines you are ineligible before any prescription is issued, you receive a full refund. There is a brief window after intake submission to cancel — text message is the fastest way to reach the team.
Does Ozari accept HSA or FSA payments?
Many HSA and FSA cards are accepted for telehealth and prescription costs. We recommend confirming with your HSA/FSA administrator, as coverage varies by plan. Contact our care team if you need an itemized receipt for reimbursement.
Pharmacy, Shipping & Legitimacy
Where does Ozari source its medication?
All medications are dispensed by licensed US compounding pharmacies compliant with state pharmacy board regulations. We do not source medication from overseas suppliers or unregulated manufacturers.
How is GLP-1 medication shipped and stored?
Medication ships in discreet, temperature-controlled packaging with cold packs. Most orders arrive within 3–5 business days via free expedited shipping. Store your medication refrigerated between 36°F–46°F, away from direct sunlight.
Is Ozari Health a legitimate company?
Yes. Ozari Health is a licensed telehealth platform operating in compliance with state and federal telehealth regulations. All prescriptions are issued by licensed physicians and filled by licensed US pharmacies. Patient health data is protected under HIPAA.
How is Ozari different from Hims, Ro, or Noom?
Ozari is a GLP-1-focused telehealth platform offering compounded semaglutide and tirzepatide plus branded options including Ozempic, Wegovy, Mounjaro, and Zepbound — starting at $86/month. Unlike general wellness platforms, every Ozari patient receives direct, ongoing access to a licensed provider for dose management and clinical support throughout treatment.
How do I contact Ozari Health with questions about my treatment?
Enrolled patients can message their provider directly through the secure patient portal. For general inquiries, visit the Contact page at ozarihealth.com. For urgent shipment or prescription questions, text message is the fastest way to reach the care team.